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Female sex (75% of reported cases)

doi: 10.1016/j.neuron.2014.12.032 245 MoritaM.Ikeshima-KataokaH.KreftM.VardjanN.ZorecR.NodaM.et al

Activation of the immune system through oxidative stress and neuroinflammation could mediate the effects of psychotic risk [105]

You'll need to explain the rationale for the limited scope of SP studies and outline plans for more comprehensive studies as development progresses

The most frequently reported side effects of tirzepatide are gastrointestinal in nature, consistent with the drug class mechanism of slowing gastric emptying
