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Cell 66 , 12791287 (1991)
doi:10.1002/jor.21559 248
Oxidative metabolites of curcumin inhibit IKK
An imbalance between the supply and demand of oxygen [141,142,143] in the arterial wall leads to a hypoxic plaque microenvironment, mainly arising from the combination of increased cellular metabolic demand and reduced oxygen diffusion caused by thickening of the arterial wall during the development of atherosclerotic lesions [144]
It is highly likely that cysteine and/or homocysteine have a significant effect on the association of low GSH with stroke severity, but the limited sample size of this study did not allow such an analysis
