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8C)(Solak et al., 2021)

Typical neuropathological features of AD include the deposition of beta-amyloid (A) into neuroinflammatory plaques, intracellular aggregates of Tau protein in neurofibrillary tangles, synaptic loss, neuroinflammation, and neuronal death

Effective melasma treatment includes removal of the excess melanin in the epidermis and dermis as well as suppression of further melanogenesis

Briefly, the MiaPaCa2 tumor-bearing mice received either vehicle (HPCD) alone or 200 mg/kg CB-839 by oral gavage twice a day for 4 days, with or without a single sub-efficacious dose of -lap at 25 mg/kg IV on day 4

doi: 10.3390/nu10030343 19