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oleifera leaf extract (150 and 250 mg/kg) presented a significant reduction in the concentration of LH, which was approximately 0.7- and 0.30-fold greater than that in the CP group, respectively (Fig

Ferritin, a 24-subunit nanocage complex comprising ferritin light chain (FTL) and ferritin heavy chain 1 (FTH) polypeptides, functions as the primary intracellular iron storage protein to inhibit ferroptosis at the cellular level through two key mechanisms: (1) iron sequestration: the ferroxidase activity of FTH causes up to 4,500 iron atoms to mineralize within its cavity and oxidize Fe 2+ to Fe 3+

Peripheral-central immune crosstalk in Parkinson's disease and its association with clinical severity

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