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The pathological changes of blue light damage to the ocular surface, crystalline lens, and retina mentioned above may lead to various eye diseases, such as keratitis, dry eye syndrome, cataracts, myopia, and age-related macular degeneration (Figure 1)

Induction of ferroptosis through inhibition of glutathione peroxidase 4 (GPX4) GPX4 plays a critical role in the cellular peroxidase system, inhibiting the formation of peroxides and thus acting as a key regulator of ferroptosis

The most significant damage occurred in the cerebrum, where neuronal degeneration was evident, characterised by cell swelling, vacuolisation, and loss of neurons

Supplying the two as separate vials is the format that respects both compounds kinetics

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