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Such mechanisms can lead to cell apoptosis/necrosis, further tissue damage, and the formation of various immunocomplexes

There is also variable expression of epithelial membrane antigen, glial fibrillary acidic protein, and Leu-7

Nicotinamide adenine dinucleotide (NADH) and acetyl-CoA, two metabolic intermediates produced in the course of FAO, induce activation of PDK, which in turn phospho-inactivates the E1 subunit of the PDH complex, leading to lower rates of glucose oxidation and higher rates of lactate release 70
