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Therefore, while metabolism-targeted combination therapies are being advanced, a systematic evaluation of their risk-benefit ratios is necessary to overcome the aforementioned limitations through rational design

Nonalcoholic fatty liver disease in women with polycystic ovary syndrome

Because L-carnitine is known to be an essential co-factor in fatty acid and energy metabolism, and patients on dialysis tend to be malnourished, it might follow that repletion of L-carnitine by the intravenous or oral route could improve nutritional status, particularly among patients with low dietary L-carnitine intakes

Carnitine palmitoyltransferase 1 increases lipolysis, UCP1 protein expression and mitochondrial activity in brown adipocytes