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Brain Res 564: 3136

Conversely, PDE10A inhibition reduces D 2 receptor activity, which has the potential to alleviate positive symptoms ( 1 and D 2 receptor signaling ( 84 (Zinc41306568) , a dual PDE1B/PDE10A inhibitor, was evaluated for its pharmacological efficacy and safety in a rat model of schizophrenia

The very long-term effects of these agents are however unknown and using them as bridging treatments to optimize patient status prior to HSCT is an attractive option

[DOI] [PubMed] [Google Scholar] Raja G

Blood 138 , 689705 (2021)
