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10.1042/bj0150286 [DOI] [PMC free article] [PubMed] [Google Scholar] 11.Hopkins FG

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Furthermore, a statistically significant difference in genotype frequencies was observed when the population was stratified by steatosis and nonalcoholic steatohepatitis (NASH) ( Cytochrome P450 family 1 subfamily a member 1 Cytochrome P450 (CYP) enzymes, specifically the CYP1A subfamily constitute a diverse group that plays pivotal roles in metabolizing both, internally generated (endobiotic) and foreign (xenobiotic) substances within the human body ( CYP1A1 belongs to this subfamily and it is mainly in extrahepatic tissues where it participates in the metabolism of a vast number of endobiotics and xenobiotic such as toxins and drugs