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10.1016/j.jconrel.2021.08.055 35 HaoZ.LiH.WangY.HuY.ChenT.ZhangS.et al (2022)

It consists of three amino acids: Cysteine, Glutamic Acid, and Glycine

Such a non-protein cofactor is known as a "prosthetic group." R -lipoic acid functions as a prosthetic group for the biological activity of the following multienzyme complexes: The glycine cleavage system that catalyzes the decarboxylation of glycine coupled with the addition of a methylene group (-CH 2 ) to tetrahydrofolate to form 5,10-methylene tetrahydrofolate, an important cofactor in the synthesis of nucleic acids ( Figure 3 )

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doi: 10.3390/nu9070702