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Kanekura K, Ma X, Murphy JT et al (2015) IRE1 prevents endoplasmic reticulum membrane permeabilization and cell death under pathological conditions

Curr Opin Genet Dev 7:7579 Bourne HR, Sanders DA, McCormick F (1991) The GTPase superfamily: conserved structure and molecular mechanism

By week 10, the patients nephrotic syndrome had resolved, leading to the discontinuation of tacrolimus and steroids at week 16

The phase 2 T2D trial similarly reported a safe and well-tolerated profile

Selvam R (2002) Calcium oxalate stone disease: role of lipid peroxidation and antioxidants
