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In the second stage, sealed envelopes were used to further allocate participants into one of three groups: a single DPSC injection (1 10 cells/injection), a double DPSC injection (1 10 cells/injection, administered twice at a 30-day interval), or a saline injection

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However, monotherapy with the Hh pathway inhibitor vismodegib did not show any significant antitumor activity in patients with ovarian cancer in a phase II clinical trial (NCT00739661) [189]