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The glycohydrolysis of NAD + is the primary catalytic reaction that cleaves the glycosidic bond within NAD + to generate NAM and ADP-ribose, whereas the ADP-ribosyl cyclase activity generates cyclic ADP-ribose (FIG

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10.1016/j.neuron.2017.02.022 [DOI] [PMC free article] [PubMed] [Google Scholar] 26.Kwong AK, Chen Z, Zhang H, Leung FP, Lam CM, Ting KY, et al

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