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Hierarchical clustering of commonly engaged proteins by the fold increase in target engagement in senescent versus non-senescent conditions (referred to as senescence selectivity) identified broadly highly-reactive proteins, clusters of proteins with specificity to certain chemotypes and others (such as GPX4) that were enriched in probes related to three different SCLAs (Fig

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105 Meanwhile, TiO 1.47 @C synthesized by direct oxidation of Ti 3 C 2 MXene showed little change in the efficiency of Fenton-like reactions after five reactions, which demonstrates its high recyclability