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In the current study, we utilized a transgenic mouse model to elucidate the role of GSH in hepatic responses to chronic ethanol consumption and explored underlying mechanisms

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Methods Islets from mice constitutively expressing fluorescent sensors reporting on cyclic AMP and Ca 2+ in both alpha and beta cells were imaged using stimuli to mimic the post-prandial state of a meal consisting of glucose and amino acids

Independent domains To ferret out how the mitochondria does it, the researchers used a combination of biochemical studies, computational methods, and genetic screens to discover that SLC25A39 is both a sensor and a transporter at the same time, Birsoy explains

Meng Q, Wang A, Hua H, Jiang Y, Wang Y, Mu H, Wu Z, Sun K