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The opposite of this mechanism is the heterolytic fission in which, after a covalent break, one atom receives both electrons (this gives a negative charge) while the other remains with a positive charge.Lipid peroxidation leads to the breakdown of lipids and to the formation of a wide array of primary oxidation products such as conju- dienes or lipid hydroperoxides, and secondary products including MDA, F2-isoprostane or expired pentane, ethane or hexane

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Foxc2 alleviates Ox-LDL-induced lipid accumulation, inflammation, and apoptosis of macrophage via regulating the expression of Angptl2