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Both promote repair, but through different routes, which is why researchers combine them
Pakos-Zebrucka K, Koryga I, Mnich K et al (2016) The integrated stress response
Viral RNA sensing (signal 1) by nucleotide-binding oligomerization domain-containing 2 and retinoic acid-inducible gene I can induce transcription of genes that encode components of the NLRP3 inflammasome
doi: 10.1016/s0378-8741(99)00174-9
