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Sleep deprivation can interfere with the production of melatonin and disrupt the body's normal sleep-wake cycle which can in turn lead to problems such as fatigue, irritability, and difficulty concentrating

(Hangzhou)

Den Krperzellen steht so tglich nur ein Bruchteil der eingenommenen Wirkstoffe zur Verfgung, obwohl gerade in Stress und Bedarfsphasen ein schnelles Auffllen der Zellspeicher besonders wichtig wre

7 Clinical outcomes of pharmacotherapy To date, numerous clinical studies including double- or single-blinded randomized clinical trials and split-face studies have been conducted to assess the therapeutic effect of various topical conventional and novel formulations in melasma management as summarized in Table 3

*Correspondence: Gaobo Yu, [email protected] These authors have contributed equally to this work This article was submitted to Plant Metabolism and Chemodiversity, a section of the journal Frontiers in Plant Science Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers