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In the biological process category, a large number of DEGs were related to response to stimulus, metabolic process, cellular process, and biological regulation (Fig

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2.2.2 Endoplasmic reticulum: regulator of lipid metabolism and redox homeostasis The ER maintains cellular homeostasis through protein synthesis, lipid metabolism, and calcium storage ( - localized to the ER membranemediates cystine import for GSH synthesis (66)