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Eric Topol of Scripps Research Translational Institute was more direct: "These peptides have no data to support their safety and efficacy." The clinical proponents argue that the FDA's safety concerns immunogenicity risk, impurity risk, organ toxicity are theoretically valid but speculative in practice
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The long-lasting influence of S protein on cerebrovascular function is unknown and should be investigated in future studies, especially considering the longevity of brain endothelial cells
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