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Current treatments for PDPN primarily rely on pharmacological and non-pharmacological interventions

Treating vitamin B12 deficiency Vitamin B12 deficiency anaemia is usually treated with injections of vitamin B12

a vitamin D deficiency has been observed in many autoimmune disorders

Methods Study design and sampling technique This observational analytical study employed a case-control design

These pre-clinical studies attributed the recovery in symptom profile to modulation of glucose transport, over-expression of mitochondrial genes, bypassing defective pathways of ETC (electron transport chain), and improvement in mitochondrial biosynthesis, modulation of microbiota, regulation of brain neuronal networks, and promoting synthesis of white matter in the brain [168]