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Prunes preserve hip bone mineral density in a 12-month randomized controlled trial in postmenopausal women: the Prune Study

In my experience following hormone optimization protocols for years, poor response more often reflects suboptimal lifestyle factors than compound or dosing issues

Commonly reported adverse effects are generally mild and may include local injection site reactions when administered via parenteral routes

Cyclic ADP-ribose production by CD38 regulates intracellular calcium release, extracellular calcium influx and chemotaxis in neutrophils and is required for bacterial clearance in vivo

Keremi et al
