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pylori infection, in which multiple cell death mechanisms interact with other cellular processes, effective therapies will likely include combinations of agents targeting different cell death programs, as well as molecules that affect additional cellular pathways

MSNs stand out as competitive carriers for drug loading due to their customizable pore sizes and significant pore volumes
Another solution when previous options have proven insufficient for pain and disease control is represented by aromatase inhibitors, which locally suppress estrogen synthesis, inducing a hypoestrogenic state

These results open new perspectives in developing non-opioid, non-NSAID pain management strategies with a safer physiological profile

DOI: 10.1016/S0140-6736(21)01751-7