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Lastly, Most clinical studies have shown that MMDD has a significant effect in the treatment of pulmonary fibrosis, but it does not mention its adverse reactions, because some traditional Chinese medicine will lead to liver injury in the treatment of diseases, such as Pinellia has hepatotoxicity, and the material basis and mechanism of hepatotoxicity are not yet clear, so the clinical use of MMDD should not only consider the severity of the patients condition, but also consider the hepatotoxicity of Pinellia

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ATAC-sequencing The ATAC libraries were generated as described previously 18 , following the Omni-ATAC protocol

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Glutathione Glutathione is found at high concentrations in the lens (3.55.5 mmol/g wet weight), especially in the epithelial layer

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87 ChenWYZhangJGhareSBarveSMcClainCJoshi-BarveS

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Nature (2013) 496(7444):23842

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