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High intra-mitochondrial ROS level can damage the mitochondrial DNA, causing global DNA hypomethylation, by decreasing the activity of DNMTs and these changes are transmitted to the progeny of the irradiated cells [124]

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have studied the effects of carnitine on GBM cells

Importantly, in a human phase II study using a recombinant IL-22 fusion protein (F-652), clinicians observed improved clinical scores as well as decreased liver injury markers when patients with ALD were treated with recombinant IL-22 (72, 73)

Inhibition of CDK1 overcomes oxaliplatin resistance by regulating ACSL4-mediated ferroptosis in colorectal cancer