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Description
Chondrocytes, the only cellular component of cartilage, maintain the dynamic equilibrium of the extracellular matrix (ECM) through precise regulation of collagen type II and matrix-degrading enzyme secretion ( In mouse models of OA, typical characteristics of ferroptosis have been observed in chondrocytes, including abnormal iron metabolism, lipid peroxidation, and mitochondrial dysfunction (Yao et al., 2021)
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The first results from complete loss of the NF1 gene along with multiple contiguous genes and occurs in 4-5% of patients with NF1 26
V.AbuhaliqaM.SyedN.AhmedI.El AnbariM.BastakiK.et al (2022)
Riyazuddin R, Bela K, Horvth E, Rig G, Gall A, Szabados L, Fehr A, Csiszr J (2019) Overexpression of the Arabidopsis glutathione peroxidase-like 5 gene (AtGPXL5) resulted in altered plant development and redox status
