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Shirkhani A

Concurrently, Ca 2+ overload activates calcium-dependent proteases (e.g., calpain) and phospholipases (e.g., Phospholipase A2 (PLA2)), which degrade cytoskeletal proteins (e.g., actin, tubulin) and membrane phospholipids, ultimately resulting in plasma membrane rupture [175]

Moreover, britanin, a bioactive terpenoid extracted from Inula lineariifolia , increased intracellular GPX4 and GSH levels and diminished ferroptosis-induced MIR injury via AMPK/GSK3/Nrf2 signaling [90]

These are all growth-related molecules.[ref] Interleukin-1 (IL-1) is an inflammatory cytokine that can inhibit REST, which is a tumor suppressor

[Abstract] Mol Cell Endocrinol