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Thus the cirrhosis dysbiosis ratio was established, in which a lower ratio is associated with greater morbidity and mortality.18,19 At present, only Chen and his research group have been able to reproduce the fecal microbiome of the cirrhotic patient.20 That is important because each population is different, and thus the predominant microbiota should be the focus of potential therapeutic targets

Acknowledgements CW was supported by an Australian Government Research Training Program (RTP) Scholarship

Its compact design has enabled laboratory studies using fluorescent tags without disrupting its core activity

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Alternatively, they may exhibit darker pigmentation in the background of an otherwise uniformly pigmented nevus