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These risks are exactly why an intramuscular injection is safer given by a trained clinician than self-administered at home

The Mayo Clinic explains: If you have had surgery or have been on bed rest for other reasons, try to get moving as soon as possible

We divide DVT into two categories: provoked and unprovoked. Provoking risk factors include: not getting up to move around very much during extensive travel major surgery causing vascular injury, prolonged hospitalization and/or limited mobility trauma fractures, such as a broken leg or rib malignancies requiring active treatment medications, such as estrogen therapy high body weight pregnancy smoking inherited conditions such as factor V Leiden, antiphospholipid syndrome and autoimmune disorders

And here's the surprising part: it's far more common than most people think

However, baseline homocysteine levels tend to be lower in people with Down syndrome than people without Down syndrome