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[DOI] [PubMed] [Google Scholar] 40.Van Hattem S, Spoo JR, Horvth B, Jonkman MF, Leeman FW

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The absence of adverse effects in rodent models is a promising indicator, not a guarantee of equivalent safety in human subjects

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It binds TrkB receptors and activates Akt and ERK signaling in hippocampal neurons
