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The ribT function remained unknown until recent research showed that its enzyme is a member of GCN5-related N-acetyltransferase, which transfers the acetyl group from acetyl-CoA to a variety of substrates (Srivastava et al., 2018

[35] Moreover, MET inhibitors, such as Crizotinib or PF-04254644, have been tested by short-term treatments in cellular and preclinical models, and have been shown to induce cardiomyocytes death through ROS production, activation of caspases, metabolism alteration and blockage of ion channels

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Ambrosio AL, Boyle JA, Aradi AE, Christian KA, Di Pietro SM

ROS generated in redox cycling contributes to anticancer activity of vitamin K