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Joint drug signal mining and risk factor analysis The present study examines the effects of VPA in conjunction with commonly used antiepileptic drugs and antipsychotics (LEV, TPM, OLZ, QTP) on HE, utilizing signal mining and risk factor analysis of co-administration
Therefore, the main mechanisms and potential implication of therapies under investigation have shifted to the early brain injury, cortical spreading depolarizations, and neuro inflammation
The liver then oxidizes this TMA into Trimethylamine N-oxide (TMAO), a metabolite strongly associated with an increased long-term risk of atherosclerosis and cardiovascular disease
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