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Regulation of gamma-glutamylcysteine synthetase subunit gene expression: Insights into transcriptional control of antioxidant defenses

doi:10.1155/2016/9409363, 2016
Step 3: MTHF releases its methyl group via vitamin B12 to the methionine cycle, which produces THF again and restarts the cycle

Covalent binding NAPQI is believed to exert its toxic effects by binding covalently to liver proteins leading to protein denaturation and necrosis of liver cells[6, 26, 27]

ascorbate peroxidase (APX) and catalase (CAT), both of which decompose HO into water
