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E., Byrne, D

4.3 Energy metabolism dysfunction Patients with HF typically exhibit features of inadequate cardiac energy metabolism, primarily because of reduced mitochondrial oxidative capacity (Lopaschuk et al., 2021)

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The continuous production of ROS forces the body to consume excess host energy just to survive the biochemical onslaught, directly contributing to the systemic, debilitating fatigue that characterizes these conditions

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