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Robert Cushman, head of Health Canada's biologic and genetic therapies directorate
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212 FBXO31 enhances cisplatin-induced ferroptosis in cholangiocarcinoma cells and stem cell-like cells, and the mechanism may be related to increased GPX4 ubiquitination and proteasome degradation, which could be reversed by GPX4 overexpression
Johann K, et al
Sprague-Dawley rats were anaesthetized with pentobarbital (40 mg/kg, i.p.)
