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Same principles apply

Specifically, robust evidence from large-scale, multicenter randomized controlled trials is still needed to conclusively establish efficacy, determine optimal dosing and timing strategies, and fully evaluate safety before widespread clinical adoption in RDS management can be recommended

Estruch R, Martinez-Gonzalez MA, Corella D, et al

Neurobiol Dis 170:105766 Hoglund E, Overli O, Winberg S (2019) Tryptophan metabolic pathways and brain serotonergic activity: a comparative review
Moreover, we found that colistin-induced depolarization is sensitive to cyclosporin A, a potent inhibitor of mitochondrial cyclophilin D (CyPD), one of the components of the mPTP, whose expression and function are required for the onset of the permeability transition 49
