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Science 287 , 10401046 (2000)
We start from where you are and we build toward where you want to go
What if you use a different amount of water
Foremost, Level 2 evidence, encompassing randomized controlled trials (RCTs) and systematic reviews with meta-analyses, offers the most robust validation
We have shown previously that sirtuins SIRT1 and SIRT3 have anti-fibrotic function, and their decreased tissue expression observed in skin biopsies from SSc patients, might directly contribute to the persistence of fibrosis 28,29
