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Alternatively, Glu is further metabolized by Glu dehydrogenase and/or aminotransferases to -ketoglutarate, which then enters the Krebs cycle generating ATP and serving as an anaplerotic source of carbon for the formation of non-essential amino acids and lipids

By supporting the immune system, it enhances the body's defence mechanisms, contributing to overall well-being

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Ongoing structure-activity relationship studies focus on optimizing chelate stability and tumor penetration, with heterobimetallic complexes and nanoparticle formulations showing particular promise for enhancing bioavailability and reducing off-target effects [125]