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Description
Accepted: June 22, 2013

Advanced glycation end-products (AGE) are the result of non-enzymatic addition of glucose or other saccharides to proteins, lipids, and nucleotides
These microclots, which are resistant to fibrinolysis, may trigger oxidative stress and the secretion of proinflammatory cytokines, establishing a vicious cycle that may be implicated in the plethora of clinical manifestations observed in LC [94,204,251]
Edinburgh: Elsevier

and inhibiting lipopolysaccharide-induced NF-B p65 translocation and mitogen-activated protein kinase phosphorylation in dendritic cells, thereby reducing inflammation [125, 228]
