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Reactive nitrogen species (RNS), particularly nitric oxide (NO), are generated via the reduction of nNOS, inducible NO synthase (iNOS), nitrate, and nitrite, and serve as key mediators of oxidative stress ( BL can neutralize both extracellular and intracellular nitrosation reactions (Figure 1)

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doi: 10.1080/0886022X.2024.2376930 20 WinnicaDEMonzonAYeSVladarEKSaalMCooneyRet al

Pioneering non-invasive collection techniques in dermatological metabolomics, such as sweat analysis, have led to the identification of unique metabolites linked specifically to conditions like psoriasis, offering new biomarker candidates (119)