glutathione peroxidase heme Frontiers Glutathione peroxidase 4: a new
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To determine whether SIRT2-regulated GSH synthesis depends on GCLC, we depleted SIRT2 by shRNA in GCLC knockdown CAKI-1 cells, and found that SIRT2 silencing decreases cellular GSH level in control cells but not in GCLC knockdown cells (Fig
JOR Spine 3 , e1123 (2020)
Plasma and urinary F2-isoprostane markers of oxidative stress are increased in cats with early (stage 1) chronic kidney disease
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It also prevented A-mediated cytotoxicity of neuro-2a neuronal cells, suggesting it could be a useful drug to stop inflammatory neurodegeneration caused by A [106]
