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Lancet 373(9669):10971104 Druker BJ et al (2006) Five-year follow-up of patients receiving imatinib for chronic myeloid leukemia

Methodological quality and risk of bias of included studies were evaluated by Jadad scale and Cochrane risk of bias tools, respectively

Various studies targeting ER stress signaling pathways and components of the UPR have demonstrated that CHAC1 expression is upregulated downstream of the ATF4-dependent signaling pathway (Figure 4)
228 , e13399 (2020)
While our bodies are designed to create it, factors like age, environmental stressors, and diet can influence our internal levels
