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The sixth coordination site, the reactive center, is variable, being a cyano group (CN), a hydroxyl group (OH), a methyl group (CH 3 ) or a 5-deoxyadenosyl group

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[DOI] [PMC free article] [PubMed] [Google Scholar] Huang JX, Lee G, Cavanaugh KE, Chang JW, Gardel ML, Moellering RE High throughput discovery of functional protein modifications by Hotspot Thermal Profiling