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NOS activity produces NO gas that reacts non-enzymatically with cysteine residues in glutathione, major non-protein thiol and protein-thiols to form S-nitrosoglutathione (GSNO) and S-nitrosothiols in a process known as S-nitrosation

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152 Following the administration of NBDHEX, GSTP1 dissociated from both the GSTP1-JNK and GSTP1-TRAF2 complexes, indicating inhibition of GST activity