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Published preclinical data in rodents suggests doses equivalent to 200mg+ in humans produce off-target effects on folate metabolism and S-adenosylmethionine (SAMe) pools

Seek medical advice for persistent bowel changes, blood in stools, unexplained weight loss, or severe abdominal pain
Individuals may also experience improved skin health, as Vitamin B12 supports cell regeneration and combats oxidative stress

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This condition, known as melena, can stem from the surgery itself or the patients health before surgery
