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3 The succinimidyl thioether bond is rapidly formed by Michael addition of a thiol to the maleimide group, making it a popular choice for conjugating a peptide to a drug

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doi: 10.1038/jid.2014.75 76 SadekKMShibNATaherESRashedFShukryMAtiaGAet al

Traditionally, fermentation has been performed in bags made with animal hides, which are regularly shaken to ensure that the milk and kefir grains are well mixed [12,90]