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All mice were kept and cared for at Centralized Animal Facilities (CAF) at PolyU

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On the other hand, such solvation anomalies are not expected to persist across more than one functional group, hence solvent-to-solvent correlation for p K a values across functional groups is rather poor (Tables 4, 5, 6, 7, 8, 9)

By generating mice with astrocytic or hepatocytic ALDH2 deficiency, Jin and collaborators showed that acetate derived from centralrather than peripheralethanol metabolism primarily drove the synthesis of gamma-aminobutyric acid (GABA), the most common inhibitory neurotransmitter in the brain after low-dose ethanol administration

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