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Supplementary information Supplementary Table 1 (download XLSX Sample sizes ( n ) and statistical significance values ( P values) for all data panels in the study

Indole-3-acetic acid (IAA), produced by gut microbiota, alleviates fibrosis by suppressing PI3K/AKT/mTOR signaling, enhancing autophagy, and reducing fibroblast activation and epithelial senescence [114]

some protocols titrate further to 12.515 mg if well tolerated [2]