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Furthermore, changes in gene expression represent only one component of the cellular response to high ambient temperatures

This effect is achieved by the lowering of blood pressure in cases of diabetic patients, decreasing oxidative stress on the sensitive sperm cells, and therefore minimizing damage to their DNA cargo

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Therefore, antioxidant therapies aimed at reducing oxidative stress represent a promising approach for protecting the BBB and mitigating cognitive decline (Rochfort et al., 2014)