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Another study demonstrated that oral exposure to high doses of Mn during the first 20 days of postnatal life reduces dopamine release later in young adolescent rats (Conley et al., 2020)
In addition, although GPx1 levels and activity were unchanged like AD cortex ( Extended Data Fig

For the first time, Altman and Das 52 proposed the existence of newly generated neurons in the hippocampus of postnatal rats in the 1960s, but this study was ignored by the scientific community

Therefore, elevated Mg levels in this region could be a contributing factor to reduced anxiety, although this hypothesis requires further investigation
